Tag Archive: Environmental Monitoring

Non-Sterile Pharmaceuticals: Next Steps After Finding an Environmental Isolate

You’ve identified an organism in your environment. Now what? If you work in a non-sterile pharmaceutical manufacturing laboratory, chances are you’ve encountered this question. You know environmental monitoring doesn’t stop at detection, but what are the correct next steps to…
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Environmental Isolate Case File: Corynebacterium spp.

Everyone has heard of diphtheria, but this familiar infection caused by a Corynebacterium strain isn’t the only illness laboratories should be concerned about. Sterile manufacturing facilities should also be on the lookout for non-diphtherial Corynebacterium. These strains, commonly found in…
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Environmental Isolate Case File: Cronobacter sakazakii

Cronobacter sakazakii, formerly Enterobacter sakazakii, is a gram-negative bacterium that belongs to the Enterbacteriaceae family. It is found in the environment, commonly on plant and organic materials, and can survive very dry conditions. The bacterium has been isolated from dry…
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The Scoop on Ready-to-Eat Foods and Listeria monocytogenes

When summer is in full swing, many of us choose to cool down with sweet frozen dairy treats. However, the thought of ice cream tainted with Listeria monocytogenes may cause anyone, especially those in susceptible populations, to think twice. Listeria…
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Environmental Isolate Case File: Cladosporium cladosporioides

Cladosporium cladosporioides, although generally nonpathogenic, can cause illness. This species, along with Exserohilum rostratum and Aspergillus fumigatus, was one of the pathogens isolated during a multistate outbreak of fungal meningitis due to contaminated sterile medication manufactured by the New England Compounding…
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Environmental Isolate Case File: Pluralibacter gergoviae

Pluralibacter gergoviae can cause big headaches in cosmetic industry laboratories. It is an opportunistic pathogen that has repeatedly been isolated from personal care products. Recently, 15,000 tubes of a popular skin cream product were recalled due to contamination with the…
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Environmental Isolate Case Files: Legionella pneumophila

There are about 20 outbreaks of Legionnaires’ disease each year in the United States.  Most outbreaks occur in buildings with large water systems such as hotels and hospitals. The outbreaks are caused by Legionella pneumophila, a harmless microorganism in a…
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Environmental Isolate Case Files: Serratia marcescens

In 1950, a United States Navy ship spent six days spraying Serratia marcescens into the air two miles off the coast of San Francisco. The spraying was part of a biological weapon test called Operation Sea Spray. Prior to the…
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Environmental Isolate Case Files: Listeria monocytogenes

Ubiquitous in nature, Listeria monocytogenes can be found in many contamination sources making it difficult to eliminate from food processing facilities. Characteristics, such as the ability to grow at refrigerator temperatures, form biofilms, thrive in moist conditions, and remain viable in high…
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Environmental Isolate Case Files: Ralstonia pickettii

If your manufacturing processes utilize purified water or highly purified water, Ralstonia pickettii should be on your list of microorganisms to control. In fact, it has become a microorganism of concern to sterile drug manufacturers because it is capable of passing through…
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